CBD’s Relevance to Schizophrenia
Schizophrenia is a disorder that generally requires heavy antipsychotic drugs just to manage daily life. However, this systematic review notes that such drugs “provide limited cognitive benefits,” which is extremely rough given the side effects antipsychotic drugs can have. As discussed in the review, CBD may be a possible alternative to such heavy prescription drugs.
CBD has both anti-inflammatory and anti-psychotic characteristics. Thus, the aim of the review was to evaluate literature (both preclinical and clinical) on the effects of CBD in relation to schizophrenia. The authors looked through 27 articles from the past 26 years.
The overarching theme of the literature demonstrated that CBD “improves cognition in multiple preclinical models of cognitive impairment,” which includes:
- Alzheimer’s disease
- Neuro-inflammatory conditions (e.g.: Fibromyalgia)
- Neurological disorders (e.g.: Epilepsy)Due to the lack of clinical evidence, the level and effectiveness that CBD might have cannot be clearly stated. The review is nonetheless an excellent starting point for the future use of CBD in neurological treatments.
Authors: Osborne AL, Solowij N, Weston-Green K; Illawarra Health and Medical Research Institute, University of Wollongong